Images are for illustration. Batch-specific photos and a sample COA are available on request.
A single-molecule flavanonol antioxidant for supplements, functional beverages and cosmetic formulations. The central formulation constraint is low aqueous solubility (<1 mg/mL) — grade selection and delivery strategy determine whether this molecule works in your system.
Release testing per batch. All safety parameters are reported on the COA. Grades 90% and 95% share the same safety profile with adjusted assay limits.
Process: Ethanol/water extraction from Larix wood/root, followed by purification, drying and milling. No Class 1 solvents are used. Detailed process flow and CCP parameters are available under NDA.
| Parameter | Specification / Method | Note |
|---|---|---|
| Assay | ≥ 98.0% (HPLC, dry basis) | 90% / 95% grades available |
| Detection | 290 nm (primary), 327 nm | HPLC‑UV quantitation |
| Appearance | Off‑white to pale yellow fine powder | No visible foreign matter |
| Particle size | ≥ 95% through 80 mesh | 100 mesh on request |
| Loss on drying | ≤ 5.0% | — |
| Ash | ≤ 5.0% | — |
| Total heavy metals | ≤ 10 ppm | — |
| Lead (Pb) | ≤ 0.5 ppm | Aligned to CN novel food notice |
| Arsenic (As) | ≤ 0.3 ppm | — |
| Mercury (Hg) | ≤ 0.1 ppm | — |
| Cadmium (Cd) | ≤ 0.5 ppm | — |
| Total aerobic count | ≤ 1,000 cfu/g | — |
| Yeast & mould | ≤ 100 cfu/g | — |
| E. coli / Salmonella / S. aureus | Not detected | Per 25 g |
| Ethanol residue | Well below ICH limit (< 5,000 ppm) | Ethanol/water extraction |
Additional tests (pesticides, PAH, allergen statement, non‑GMO statement) available on request. The sample COA above shows a representative impurity profile — use it to compare against your current material.
Dihydroquercetin is practically insoluble in water and soluble in ethanol. This is not a defect — it is a constraint that determines which dosage forms are straightforward and which require engineering.
| Dosage form | Constraint | Viable engineering path |
|---|---|---|
| Hard capsule / tablet | Solubility is not limiting in dry state. | Direct use of 80–100 mesh powder; control blend uniformity and compression stability. |
| Softgel / oil‑based | Water‑insoluble but soluble in ethanol and organic solvents. | Phospholipid complex or oil‑based suspension system. |
| Beverage / aqueous | < 1 mg/mL in water; direct addition precipitates at meaningful doses. | Microencapsulation, emulsion, or solubilizer carrier. Or switch to the 50% grade above. |
| Cosmetic (topical) | pH and light sensitivity in formulation. | Avoid high‑pH systems; consider photoprotection and metal‑chelating concept. |
Key data on the page: water solubility < 1 mg/mL; ethanol ≈ 61 mg/mL; sensitive to strong alkali,
strong oxidants and prolonged light exposure; good thermal stability in dry state.
Direct addition to clear beverages is not feasible at meaningful doses without solubilization.
For beverage applications, discuss a microencapsulated or emulsion‑based grade before formulation lock.
Two questions buyers ask before sampling: how long does it store, and how fast can it ship.
| Item | Detail |
|---|---|
| Shelf life | 24 months, sealed, protected from light, ≤25 °C |
| Long‑term | 25 °C / 60% RH, 24 months — assay and impurity profile within spec |
| Accelerated | 40 °C / 75% RH, 6 months — no significant change in key indicators |
| Sensitivities | Strong alkali, strong oxidants, prolonged light exposure; good thermal stability in dry state |
Full stability report with batch‑level data is available on request.
| Item | Detail |
|---|---|
| Stock status | ≥98% / 80 mesh — regularly stocked |
| Sample lead time | 3–5 business days |
| Standard order | 15–20 business days (quantity and packaging dependent) |
| Bulk / custom | Schedule in advance; lead time confirmed at quotation |
| Capacity | Production capacity and line details available during supplier audit or under NDA |
Lead times are indicative and confirmed at order placement.
The number on the COA is not the decision. The decision is which grade works in your specific system.
| Grade / attribute | Typical match | Why |
|---|---|---|
| ≥98% HPLC, 80 mesh | Capsules, tablets, clinical nutrition | High purity reduces excipient load; mesh suits direct blending and compression. |
| 95% HPLC, 80–100 mesh | Functional food, solid beverage, premix | Cost/performance balance; assay sufficient for label claims. |
| Microencapsulated / emulsion grade | RTD beverages, aqueous functional drinks | Resolves the solubility bottleneck; avoids precipitation and bioavailability loss. |
| Cosmetic grade (custom) | Antioxidant serum, photoprotection formulas | Metal chelation and UV‑absorption concept; confirm formula pH and light conditions. |
Microencapsulated grade is development‑stage. Contact us to discuss feasibility and MOQ before it appears as a standard catalog item.
Status applies to the ingredient under specified conditions of use. Finished‑product claims and category limits remain the formulator’s responsibility.
| Market | Status | Key condition |
|---|---|---|
| China | Novel food ingredient (Notice No. 5, 2021) | Source from cultivated Larix root; specified food categories; beverage limit 20 mg/kg. |
| USA | GRAS — FDA GRN 916 (no objection) | For defined food categories and use levels; ≥95% preparation covered. |
| EU | Novel Food authorised (2017) | Taxifolin‑rich larch extract approved under specified categories and levels. |
| Cosmetics | CN new cosmetic ingredient filing (2024) | Usable in relevant cosmetic formulas within filed scope. |
| Item | Detail |
|---|---|
| MOQ | 1 kg (sample / trial order); 25 kg standard packaging negotiable. |
| Packaging | 1 kg foil bag · 5 kg carton · 25 kg fiber drum with food‑grade PE liner. |
| Price drivers | Assay grade (95% vs 98%), mesh, microencapsulation/custom blend, order quantity, packaging, destination & Incoterms. |
| Documents per batch | COA, MSDS. TDS, allergen statement, non‑GMO statement, Halal/Kosher on request. |
| Storage | Sealed, protected from light, cool and dry; recommended ≤ 25 °C. |
Custom & OEM: Custom mesh, carrier blends (maltodextrin, phospholipid) and microencapsulated grades can be developed per project. MOQ and development timeline are confirmed at quotation. Discuss a custom specification →
No fixed price is listed. Quotation depends on the variables above — a fixed headline price would only obscure the grade and packaging assumptions behind it.
HPLC separates the molecule itself; UV measures absorbance of conjugated systems. Dihydroquercetin absorbs near 290 nm, but other flavonoid impurities can contribute signal in the same region. Our release assay is HPLC area normalization or external standard; the method is stated on the COA. UV is used for process control, not final release.
Total impurities are typically ≤ 2.0%, with any single unspecified impurity ≤ 0.5% — a common commercial specification for concentrated taxifolin. The number is not arbitrary: a stable impurity profile is a more reliable indicator of process consistency than the assay figure alone.
Yes, if added as free powder at meaningful doses in a clear aqueous system. This is precisely why raw‑material grade and formulation grade need to be distinguished. If you are formulating a beverage, please review our 50% maltodextrin grade or discuss microencapsulation before locking the formula.
Commercial material is extracted from the wood/root of Larix species (commonly Larix gmelinii or L. sibirica). The plant part affects the accompanying impurity profile — comparing the sample COA against your current material is the practical way to judge comparability.
80–100 mesh is standard. Finer mesh or blends with carriers (maltodextrin, phospholipid) can be discussed per project. Custom specifications normally require a defined MOQ and development lead‑time.
Deep dives into the technical constraints and regulatory questions that come up during formulation.
All articles are written by our R&D and regulatory team. View all technical resources →
Tell us the dosage form and target dose. We will reply with a matched grade, a sample COA and the specification sheet for that grade.
If your application is outside what we can support, we will say so directly.
